CLINICAL TRIALS DAY!
It's celebrated around the world on or near May 20 each year in order to celebrate the day that James Lind started what is often considered the first randomized clinical trial aboard a ship on May 20, 1747.
The HMS Salisbury of Britain’s Royal Navy fleet patrols the English Channel at a time when scurvy is thought to have killed more British seamen than French and Spanish arms. Aboard this ship, surgeon mate James Lind, a pioneer of naval hygiene, conducts what many refer to as the first clinical trial.
Acting on a hunch that scurvy was caused by putrefaction of the body that could be cured through the introduction of acids, Lind recruited 12 men for his “fair test.” Those allocated citrus fruits experienced “the most sudden and good visible effects,” according to Lind’s report on the trial.
Though Lind, according to The James Lind Library, might have left his readers “confused about his recommendations” regarding the use of citrus in curing scurvy, he is “rightly recognized for having taken care to ‘compare like with like’, and the design of his trial may have inspired” and informed future clinical trial design.
From ACRP Clinical Trials Day website. Posted on May 20, 2016.