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Last Updated: Jan 19, 2018 URL: http://theta.utoronto.ca/HomePage Print Guide

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HERC database of mapping studies

HERC database of mapping studiesan Excel spreadsheet listing studies mapping to EQ-5D from other patient-reported outcome measures or clinical instruments, is now available. It presents details of the sample size, modelling methods and patient population, in addition to the citation details and source instruments that are mapped in each of the 135 studies meeting the inclusion criteria. An article summarising the methods of the literature review and the results of version 2.0 of the database has been published in Health and Quality of Life Outcomes. The current version (5.0) is based on searches conducted in April 2016; the database will be updated regularly as new studies are published.

The database aims to provide a readily-accessible collection of all studies mapping to EQ-5D that is easy to search and filter. We anticipate that this will be useful for:

  • Those who wish to identify mapping studies to estimate utilities for cost-utility analyses and/or decision-analytical models constructed for publication or for submissions to health technology assessment (HTA) organisations, such as NICE, SMC, CADTH or PBAC.
  • Authors, editors or reviewers who wish to assess the novelty of a new mapping study.
  • Those conducting systematic reviews of methods for estimating utilities or QALYs.
  • Those seeking to identify the estimation models and sample sizes currently used in mapping studies and identify new developments for further research.

Robot-Reviewer tool

RobotReviewer, a user interface coupled with the machine learning technologies, is a system to automate the assessment of bias of randomized controlled trials using the Cochrane RoB tool. For each domain in the Risk of Bias (RoB) tool, the system should reliably perform two tasks: 1) determine whether a trial is at low risk of bias (document classification of low v high or unclear risk of bias), and 2) identify text from the trial report that supports these bias judgments (sentence classification of relevant vs. irrelevant)[…]. Conclusion: Risk of bias assessment may be automated with reasonable accuracy. Automatically identified text supporting bias assessment is of equal quality to the manually identified text in the CDSR. This technology could substantially reduce reviewer workload and expedite evidence syntheses. (Adapted from : RobotReviewer: evaluation of a system for automatically assessing bias in clinical trials.)

Automatic bias assessment for articles in the Trip Database (Robot-Reviewer website with the GitHub access to source code): http://www.robotreviewer.net/blog/2016/7/29/robotreviewer-trip

TRIP database (EBM resource): https://www.tripdatabase.com/

Blog post from TRIP database: https://blog.tripdatabase.com/2016/08/06/new-feature-automated-assessment-of-bias/

Stand alone tool: https://robot-reviewer.vortext.systems/


EQUATOR Reporting Guideline Decision Tree

EQUATOR Reporting Guideline Decision Tree

EQUATOR have created a simple flow chart to help authors, editors and peer reviewers find the most appropriate checklist and reporting guideline (Feb 2016): Selecting the appropriate reporting guideline for your article. They have also collaborated with Penelope Research to develop an online wizard based on the chart.


CEA Registry

CEA Registry (Tufts)

The CEA Registry at Tufts University is a comprehensive registry of healthcare cost-effectiveness analyses. Health-related CEAs are used to estimate in a ratio the resources used (costs) and the health benefits achieved (effects) for an intervention compared to an alternative treatment strategy. The Registry focuses on a subset of CEAs, called cost-utility analyses (CUAs) that considers both quality of life and added life years as the benefits achieved.

CIHI Patient Cost Estimator (PCE) Tool

The Patient Cost Estimator (PCE) is an interactive tool developed by CIHI to estimate the average cost of various services provided in hospitals. This tool provides information nationally, by jurisdiction and by patient age group. The cost estimates represent the estimated average cost of services provided to the average typical inpatient in an acute care facility.

Access CIHI Patient Cost Estimator (PCE) page to learn more.

Canadian Institute for Health Information (CIHI) is an independent, not-for-profit organization that provides essential information on Canada’s health system and the health of Canadians. Our stakeholders use our broad range of health databases, measurements and standards, together with our evidence-based reports and analyses, in their day-to-day decision-making. We protect the privacy of Canadians by ensuring the confidentiality, integrity and availability of our health care information.


ISPOR Education Resources

As a scientific society, ISPOR provides and promotes quality education on pharmacoeconomics / health economics and outcomes research (clinical, economic, and patient-reported) and their use in health care decisions. Our educational opportunities include videos, webinars, online training, short courses (prior to ISPOR meetings), a directory of degree and non-degree education programs in outcomes research and related disciplines around the world, as well as tools for educators.

Access ISPOR Education page to learn more.

Founded in 1995 as an international multidisciplinary professional membership society, the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) advances the policy, science, and practice of pharmacoeconomics (health economics) and outcomes research (the scientific discipline that evaluates the effect of health care interventions on patient well-being including clinical, economic, and patient-centered outcomes).  

PEDE Database

PEDE Database

Methods for the conduct of economic evaluations have evolved over time to improve the quality of evidence for allocation decisions. However, child health differs from adult health in important ways. As a result, there are aspects to the measurement of costs and consequences that are unique to the paediatric population.
The goal of the Paediatric Economic Database Evaluation (PEDE) Project is to provide tools and promote research to advance the field of child health economic evaluation.
Learn more about the database.
Check the PEDE Nesletter.

    NHS Centre for Reviews and Dissemination

    NHS Centre for Reviews and Dissemination

    The CRD is comprised of three databases; DARE, NHS EED and HTA. DARE contains 15,000 abstracts of systematic reviews including over 6,000 quality assessed reviews and details of all Cochrane reviews and protocols. NHS EED contains 24,000 abstracts of health economics papers including over 7,000 quality assessed economic evaluations. HTA brings together details of over 8,000 completed and ongoing health technology assessments from around the world.




      Patient ORiented Prostate Utility Scale (PORPUS)

      The Patient ORiented Prostate Utility Scale (PORPUS) is a tool that measures quality of life and utility for prostate cancer patients.
      Visit the PORPUS Website to learn more.


      PRISMA Flow Diagram Generator

      When reporting systematic reviews it is recommended that one provide a graphical representation of your article screening process. [see the PRISMA statement] While you can manually draw a PRISMA Flow Diagram, this manual process may become tiresome if it needs to be repeated as the review is underway. By creating a tool that automatically generates a PRISMA Flow Diagram from a simple set of information, the process of updating or adjusting these diagrams is simplified.
      The PRISMA Flow Diagram Generator can produce its output in 10 different file formats, including PNG, GIF, PDF and EPS - choose any number of formats as appropriate to your publication's requirements.
      • Leslie Dan Faculty of Pharmacy at the University of Toronto
      • Institute of Health Policy, Management and Evaluation (IHPME)
      • UHN - Toronto General Hospital

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