- Please see titles posted in News section below
- THETA Rounds will resume in September 2016, please check back for updates...
Since 2008 THETA has been hosting a lecture series THETA Rounds and inviting world experts to address various issues related to Health Technology Assessment, Clinical Research and Health Policy and Ethics fields. From January 2016 onwards THETA Rounds are available in the live webinar format. Recordings of most sessions can be accessed on the THETA Rounds Archive page.
THETA Rounds will resume in Septemeber 2016. Please check our website in August for a list of gueast speakers.
THETA Collaborative has moved to a new home…
Since THETA received the Canada Foundation for Innovation (CFI) infrastructure grant in 2013, it has taken three years for the move to finally happen. We have worked closely with architects, designers and hospital management team to plan out our new space.
Our new address is:
University Health Network, TGH Site, Eaton Building, 200 Elizabeth Street, 10EB-230
Phone # 416-634-7245, Fax # 416-340-3459
Our primary email address is still the same firstname.lastname@example.org
Posted on June 7, 2016
It's celebrated around the world on or near May 20 each year in order to celebrate the day that James Lind started what is often considered the first randomized clinical trial aboard a ship on May 20, 1747.
The HMS Salisbury of Britain’s Royal Navy fleet patrols the English Channel at a time when scurvy is thought to have killed more British seamen than French and Spanish arms. Aboard this ship, surgeon mate James Lind, a pioneer of naval hygiene, conducts what many refer to as the first clinical trial.
Acting on a hunch that scurvy was caused by putrefaction of the body that could be cured through the introduction of acids, Lind recruited 12 men for his “fair test.” Those allocated citrus fruits experienced “the most sudden and good visible effects,” according to Lind’s report on the trial.
Though Lind, according to The James Lind Library, might have left his readers “confused about his recommendations” regarding the use of citrus in curing scurvy, he is “rightly recognized for having taken care to ‘compare like with like’, and the design of his trial may have inspired” and informed future clinical trial design.
From ACRP Clinical Trials Day website. Posted on May 20, 2016.
The Society for Medical Decision Making and the NIHR Patient Safety Translational Research Centre of Imperial College London are proud to host the 16th Biennial SMDM-European Conference in London, UK, June 12-14, 2016.
THETA staff members: Valeria E. Rac, MD, PhD; Lusine Abrahamyan, MD MPH PhD has been selected to teach a short course at the prestigious SMDM-European Conference. Congratulations to all team members whose work has also been accepted for presentations at the conference.The meeting’s special focus is on “Improving Diagnostic Decision Making”, with two invited symposia on vaccination decision making and on cancer diagnostic delays. The meeting’s keynote speakers are Professor Ralph Hertwig, Managing Director of the Max Planck Institute for Human Development and Mark L. Graber, Senior Fellow at RTI International, Professor Emeritus of Medicine at the State University of New York at Stony Brook, and President of the Society to Improve Diagnosis in Medicine. Our aim is to bring together high-quality, oral and poster presentations from psychology, epidemiology, health economics and other scientific disciplines involved in the study of medical decisions.
Complex interventions for comparative effectiveness and health technology assessment – real world experience. Course Director: Valeria E. Rac, MD, PhD, Course Faculty: Lusine Abrahamyan, MD MPH PhD
Mixed method program evaluation of the telehomecare program for patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD) in Ontario, Canada: qualitative study. Gemma Hunting, MA, Nida Shahid, HBSc., CCRP, Yeva Sahakyan, MD, MPH, Iris Fan, BA, Christelle Moneypenny, Hon BA, MSc (cand.), Aleksandra Stanimirovic, MSc, PhD (cand.), Taylor North, Yelena Petrosyan, MD, MPH, PhD (cand.), Murray D Krahn, MD, MSc, FRCPC, Valeria E. Rac, MD, PhD
The role of telehomecare on blood pressure control in patients with heart failure and chronic obstructive pulmonary disease in Ontario, Canada. Valeria E. Rac, MD, PhD, Yeva Sahakyan, MD, MPH, Nida Shahid, HBSc., CCRP, Aleksandra Stanimirovic, MSc, PhD (cand.), Petros Pechlivanoglou, MSc, PhD, Welson Ryan, Lusine Abrahamyan, MD MPH PhD and Murray D Krahn, MD, MSc, FRCPC
New model of healthcare delivery: telehomecare program for heart failure (HF) and chronic obstructive pulmonary disease (COPD) patients in Ontario, Canada. Valeria E. Rac, MD, PhD, Yeva Sahakyan, MD, MPH, Nida Shahid, HBSc., CCRP, Aleksandra Stanimirovic, MSc, PhD (cand.), Iris Fan, BA, Welson Ryan, Murray D Krahn, MD, MSc, FRCPC
Diagnostic accuracy of level IV portable sleep tests versus polysomnography for sleep-disordered breathing: a systematic review and meta-analysis. Lusine Abrahamyan, MD, MPH, PhD, Yeva Sahakyan, MD, MPH, Suzanne Chung, Petros Pechlivanoglou, MSc, PhD, Steven M. Carcone, MSc, Valeria E. Rac, MD, PhD and Murray Krahn, MD, MSc, FRCPC
Posted on March 3, 2016
As of February 2, THETA began recruitment of heart failure patients and health care providers (i.e. nurses, GPs, cardiologists) involved in the Telehomecare Program, as well as Telehomecare program coordinators, administrators, and decision-makers. By means of a Delphi panel, we aim to gather consensus on opinion and choice from the panelists regarding the quality indicators that are important to the program. For the purpose of this project, we will conduct a three-round Delphi study. Each round will take approximately four weeks to complete and will include a calculated rating and summary of the list of indicators. A final list of indicators will be selected upon completion of the third round. Complete information about this study can be found here.
Posted on March 3, 2016
At the upcoming Canadian Association for Health Sevices and Policy Research (CAHSPR) Toronto Conference, from May 09 to 12, 2016, discussions will focus on the following theme: A Learning Healthcare System: Let the Patient Revolution Begin! CAHSPR’s Annual Conference is the largest gathering of health care researchers, decision-makers, and policy-makers in Canada. Featuring high-profile keynote speakers, cutting-edge panels on current issues in health care, and a wealth of networking activities, the conference is the country’s premier event for evidence-informed discussion and debate on health care.
THETA staff is contributing several oral and poster presentations at the conference:
Valeria E. Rac, Gemma Hunting Nida Shahid, Yeva Sahakyan, Iris Fan, Christelle Moneypenny, Aleksandra Stanimirovic, Taylor North, Yelena Petrosyan, Murray Krahn. Barriers and Facilitators to implementation and adoption of the Telehomecare Program for patients with chronic obstructive pulmonary disease and heart failure in Ontario, Canada.
Fiona Miller, Sarah Patton, Frieda Daniels, Austin Nam, Joanna Bielecki, Murray Krahn. Towards a better health technology innovation system: A scoping review of patient and public involvement in technology design and technology assessment.
Valeria E Rac, Josephine Wong, Kathleen Rice, Laura Teague, Sunita Coelho, Eva Haratsidis, Steven Carcone, Murray Krahn, Kevin Y Woo. Patients’ and healthcare providers’ experiences with community-based wound care services in Toronto.
Valeria E. Rac, Yeva Sahakyan, Nida Shahid, Alexandra Stanimirovic, Welson Ryan, Murray Krahn. Nurse workload and satisfaction with providing Telehomecare to COPD and HF patients in Ontario, Canada.
Valeria E. Rac, Nida Shahid, Yeva Sahakyan, Aleksandra Stanimirovic, Welson Ryan, Murray Krahn. New model of healthcare delivery - Telehomecare Program for chronic obstructive pulmonary disease (COPD) and heart failure (HF) patients in Ontario, Canada.
Posted on Feb 25, 2016 Conference description and photo adapted from CAHSPR website.
ARCC is pleased to announce that its 5th annual conference will take place from May 8th to 9th at the Hilton Toronto in Toronto, Ontario. The objective of this conference is to bridge a connection between researchers and decision-makers, using health economics, services, policy and ethics research to improve cancer control and the delivery of cancer care.
Posted on Jan 12, 2016
THETA Collaborative presents at the Society for Medical Decision Making (SMDM) 2015 - 2nd Biennial Asia-Pacific Conference, January 08 - January 10, 2016, at the Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Theme: Making Difficult Clinical and Policy Decisions: The Example of Ageing and End of Life Care in Asia-Pacific.
Much of modern medical education and research has been devoted to preventing and treating illnesses and delaying death. In comparison, there has been little attention in teaching, practising, policy making and research into patients’ death and dying – something that most health professionals face in their work; and ultimately, a reality that we all face. In medicalising the aging, terminally ill, death and dying, many discussions of end of life (EOL) decisions are ‘medicine’ focused resulting in aggressive therapies that shorten patients’ lives instead of improving them, particularly when surrounded by many uncertainties. Instead, having the best practices to adopt, implement and enable ‘person’ or ‘patient’‐ oriented decision making, can enhance people’s EOL with fulfilment, satisfaction, autonomy and dignity.
THETA staff participates this year with the following:
Pre-Meeting Short Courses
Introduction to Health Technology Assessment, Course Director: Murray Krahn, MD, Msc, FRCPC; Course Faculty: Jeremy D. Goldhaber-Fiebert, PhD
Long-Form Oral Abstracts
Understanding the Economic Burden of Care for Patients on Renal Replacement Therapy
Murray D Krahn, MD, MSc, FRCPC, Karen E Bremner, BSc, Claire de Oliveira, PhD, Stephanie Dixon, PhD, Nicholas Mitsakakis, MSc PhD, Petros Pechlivanoglou, MSc, PhD
Impact of Telehomecare on Remotely Monitored Clinical Parameters of Chronic Obstructive Pulmonary Disease and Heart Failure Patients. Valeria E. Rac, MD, PhD, Yeva Sahakyan, MD, MPH, Nida Shahid, HBSc., CCRP, Aleksandra Stanimirovic, MSc, PhD (cand.), Petros Pechlivanoglou, MSc, PhD, Welson Ryan, Lusine Abrahamyan, MD MPH PhD and Murray D Krahn, MD, MSc, FRCPC
Long-Form Oral Abstracts: Broadening the Relevance of Policy Analyses. Moderator: Murray D Krahn, MD, MSc, FRCPC
Short-Form Oral Presentations
Evaluating the Implementation and Adoption of Telehomecare Program for Chronic Obstructive Pulmonary Disease or Heart Failure Patients. Gemma Hunting, MA, Nida Shahid, HBSc., CCRP, Yeva Sahakyan, MD, MPH, Iris Fan, BA, Christelle Moneypenny, Hon BA, MSc (cand.), Aleksandra Stanimirovic, MSc, PhD (cand.), Taylor North, Yelena Petrosyan, MD, MPH, PhD (cand.), Murray D Krahn, MD, MSc, FRCPC and Valeria E. Rac, MD, PhD
New Model of Healthcare Delivery - Telehomecare Program for Chronic Obstructive Pulmonary Disease and Heart Failure Patients in Ontario, Canada. Valeria E. Rac, MD, PhD, Yeva Sahakyan, MD, MPH, Nida Shahid, HBSc., CCRP, Aleksandra Stanimirovic, MSc, PhD (cand.), Iris Fan, BA, Welson Ryan, Murray D Krahn, MD, MSc, FRCPC
Health Services for Chronic Obstructive Pulmonary Disease and Heart Failure Patients in Ontario Telehomecare Program. Valeria E. Rac, MD, PhD, Yeva Sahakyan, MD, MPH, Nida Shahid, HBSc., CCRP, Aleksandra Stanimirovic, MSc, PhD (candidate), Welson Ryan and Murray D Krahn, MD, MSc, FRCPC
Posted on Jan 8, 2016
Registration now open for two new courses offered by THETA Collaborative in February 2016
In line with its education commitment to develop and teach graduate-level courses, THETA staff have organized and will be teaching two courses:
Introduction to R for decision modelers (1-day course), Feb 12, 2016
Decision modelling using R (3-day course), Feb 16-18, 2016
Both courses will offer a webinar option. Registration is now open; last day to register: Dec 01, 2016
Posted on Nov 18, 2015
Dr. Murray Krahn recognized for his exceptional service at the 2015 SMDM Meeting
As the the Society for Medical Decision Making (SMDM) past-president and a current Board member Dr. Murray Krahn has substantially contributed to the advancement of SMDM over the years and this year at the 37th Annual North American Meeting he has been presented with a recognition award for his service.
Posted on Oct 19, 2015
Dr. Murray Krahn with Canadian and US researchers compares End-of Life costs for advanced lung cancer patients in both countries.
In his new study published in the Palliative Medicine journal, Dr. Murray Krahn and his research colleagues compares end-of-life costs in Ontario, Canada, and the United States, using administrative health data. The article: "An international comparison of costs of end-of-life care for advanced lung cancer patients using health administrative data" was also highlighted by the Faculty of Pharmacy, University of Toronto in the News Section. The authors point out that: "Our study contributes important data about costs for cancer patients at the end of life, to complement the consideration of other factors in the evaluation of models of care before dying."
Posted on Oct 19, 2015
THETA Collaborative participates in TGRI Research Day
On October 6th 2015 THETA Collaborative participated in the Toronto General Research Institute (TGRI) Research Day. "This event is a celebration of TGRI achievements in basic and clinical research and an opportunity to promote interdepartmental and cross pillar collaborations among researchers. TGRI Research Day is open to all TGRI Scientists, Clinician Scientists, trainees and staff." THETA's contribution to this event consists of nine abstracts, three of which will be showcased as posters.
Rac VE, Abrahamyan L, Pechlivanoglou P, Shahid N, Wong J, Sahakyan Y, Fan I, Hunting G, Carcone S, Stanimirovic A, Petrosyan Y, Ryan W, Chung S, Pham B, Mitsakakis N, Krahn MD Complex Interventions for Comparative Effectiveness and Health Technology Assessment.
Ieraci L, Pechlivanoglou P, Bayley M, Kapral M, Fang J, Li S, Krahn MD. Real-world effectiveness of stroke units in Ontario. A matched cohort analysis.
Bremner KE, de Oliveira C, Liu N, Greenberg ML, Nathan PC, McBride ML, Krahn MD. Costs for children with cancer, pre-diagnosis and 1-year post-diagnosis: a population-based study in Ontario
Mitsakakis N, Krahn MD, Tomlinson G. Analysis of aggregate health care cost data using Bayesian mixed models
Rac VE, Wong J, Mitsakakis N, Pechlivanoglou P, Carcone S, Krahn MD. Clinical effectiveness of the wound interdisciplinary team study
Rac VE, Shahid N, Sahakyan Y, Fan I, Stanimirovic A, Abrahamyan L, Krahn MD. Evaluating impact of Telehomecare on patient quality of life and satisfaction
Sahakyan Y, Rac VE, Fan I, Ieraci L, Hall R, Kelloway L, van Velde G, Kapral MK, Bayley M, Krahn MD. Structure and function of stroke units in Ontario in 2013-2014
Hunting G, Shahid N, Sahakyan Y, Fan I, Moneypenny C, Stanimirovic A, North T, Petrosyan Y, Krahn MD, Rac VE. Evaluating the Implementation and Adoption of Telehomecare in Ontario
Rac VE, Sahakyan Y, Shahid N, Stanimirovic A, Fan I, Ryan W, Pechlivanglou P, Abrahamyan L, Krahn M. The impact of Telehomecare on COPD and HF patient monitoring parameters
Boehme KE, Jamal M, Perlis N, Bremner KE, Alibhai S MH, Finelli A, Ritvo P, Krahn MD, Kulkarni GS. Validating the Bladder Utility Symptom Scale-Psychometric (BUSS-P)
2015 TGRI Research Day description and a banner image adapted from TGRI website. Posted on Oct 5, 2015