Toronto Health Economics and Technology Assessment Collaborative
 

Mike Paulden

Mike PauldenMike Paulden, MSc, MA (Cantab.), is a Research Associate at THETA. He was previously a Research Fellow in the Team for Economic Evaluation and Health Technology Assessment at the Centre for Health Economics, University of York. He holds an MA in Economics from the University of Cambridge and an MSc in Health Economics from the University of York.

Mike's interests are in the economic evaluation of health care technologies. He has worked on Health Technology Assessment (HTA) projects for the National Institute for Health Research (NIHR) and the National Institute for Health and Clinical Excellence (NICE) in the UK, and for the Medical Advisory Secretariat (MAS) of the Ministry of Health and Long-Term Care (MOHLTC) in Ontario. He has contributed to models evaluating the cost-effectiveness of a variety of health technologies and interventions, including formal screening programs for post-natal depression, neuromise inhibitors for the treatment of influenza and non-invasive imaging for the diagnosis of coronary artery disease.

Mike's theoretical work has focused on a number of issues which carry implications for social decision making in health care, including the perspective on social choice adopted by decision makers, the cause and effect of future growth in the cost-effectiveness threshold and the rate of time preference for health implied by health sector budget allocations. This work has addressed a long-running dispute over the use of differential discounting in cost-effectiveness analysis and has challenged current discounting practice in the UK and elsewhere.

Mike's contact details are available at mikepaulden.tel.

Publications

NIHR Health Technology Assessments

Antiviral drugs for the treatment of influenza
Burch J, Paulden M, Conti S, Stock C, Corbett M, Welton N, et al. Antiviral drugs for the treatment of influenza: a systematic review and economic evaluation. Health Technol Assess 2009;13(58). URL: http://www.hta.ac.uk/1701
PDF: http://www.hta.ac.uk/fullmono/mon1701.pdf
NICE guidance: http://guidance.nice.org.uk/TA168

Methods to identify postnatal depression in primary care
Hewitt C E, Gilbody S M, Brealey S, Paulden M, Palmer S, Mann R, et al. Methods to identify postnatal depression in primary care: an integrated evidence synthesis and value of information analysis. Health Technol Assess 2009;13(36).
URL: http://www.hta.ac.uk/1521
PDF: http://www.hta.ac.uk/fullmono/mon1336.pdf

Paulden M, Palmer S, Hewitt C E, Gilbody S M. Screening for postnatal depression in primary care: cost effectiveness analysis. BMJ 2009;339:b5203.
PDF: http://www.bmj.com/cgi/reprint/339/dec22_1/b5203
PDF (print version ) http://www.bmj.com/cgi/section_pdf/339/dec22_1/b5203.pdf
URL: http://www.bmj.com/cgi/content/abstract/339/dec22_1/b5203

Sugammadex for the reversal of muscle relaxation in general anaesthesia
Chambers D, Paulden M, Paton F, Heirs M, Duffy S, Craig D, et al. Sugammadex for the reversal of muscle relaxation in general anaesthesia: systematic review and economic assessment. Health Technol Assess 2010;14(00).
URL: http://www.hta.ac.uk/1780
PDF (available May 2010): http://www.hta.ac.uk/fullmono/mon1780.pdf

NICE Single Technology Appraisals

Alitretinoin for Severe Chronic Hand Eczema
Rodgers M, Griffin S, Paulden M, Slack R, Duffy S, Ingram J R, Woolacott N, Sculpher M. Alitretinoin for Severe Chronic Hand Eczema: A NICE Single Technology Appraisal. PharmacoEconomics 2010;28(5):351-62.
URL: http://adisonline.com/pharmacoeconomics/Fulltext/2010/28050/Alitretinoin_for_Severe_Chronic_Hand_Eczema__A.2.aspx

Theoretical papers

Discounting and decision making
Claxton K, Paulden M, Gravelle H, Brouwer W, Culyer A J. Discounting and decision making in the economic evaluation of health-care technologies. Health Economics 2010
URL: http://www3.interscience.wiley.com/journal/123421690/abstract

Paulden M, Claxton K. Budget allocation and the revealed social rate of time preference for health. CHE Research Paper 53. October 2009.
URL: http://www.york.ac.uk/inst/che/pdf/rp53.pdf

Both papers above were presented at CADTH in April 2010
Poster: http://theta.utoronto.ca/presentations/theta_cadth_2010_paulden.pdf

Paulden, M. Some problems with the UK Treasury's discount rate. THETA Working Paper 2. March 2010.
URL: http://theta.utoronto.ca/papers/THETA_Working_Paper_2.pdf

Does CEA discriminate against patients with short life expectancy?
Paulden M, Culyer A J. Does cost-effectiveness analysis discriminate against patients with short life expectancy? Matters of logic and matters of context. THETA Working Paper 1. March 2010.
URL: http://theta.utoronto.ca/papers/THETA_Working_Paper_1.pdf

The paper above was presented at SMDM Europe (oral) and HTAi (poster click here to download) in June 2010.

Email Address: mike.paulden@theta.utoronto.ca






THETA Work Product
Title Type Forum
Cost-effectiveness analysis and budget impact assessment: a graphical way to combine the two for the aid of decision makers Presentation ISPOR 2011
Gene Expression Profiling for Guiding Adjuvant Chemotherapy Decisions in Women with Early Breast Cancer: A Cost-Effectiveness Analysis of 1,000 Strategies for the Provision of Adjuvant! Online, Oncotype DX, and Chemotherapy Poster ISPOR 2011
Does cost-effectiveness analysis discriminate against patients with short life expectancy? Presentation ISPOR 2011
Cost-effectiveness of the most commonly used non-surgical treatments for non-specific (mechanical) neck pain Poster ISPOR 2011
Gene Expression Profiling for Guiding Adjuvant Chemotherapy Decisions in Women with Early Breast Cancer: A Cost-Effectiveness Analysis of 1,000 Strategies for the Provision of Adjuvant! Online, Oncotype DX, and Chemotherapy Presentation CADTH 2011
Investment and disinvestment of health technologies: why CADTH ought to adopt two cost-effectiveness thresholds Poster CADTH 2011
Investment and disinvestment of health technologies: the need for two cost-effectiveness thresholds Presentation Economic Evaluation Seminars
Investment and disinvestment of health technologies: the need for two cost-effectiveness thresholds Presentation INFORMS Healthcare 2011
Gene Expression Profiling for Guiding Adjuvant Chemotherapy Decisions in Women with Early Breast Cancer: A Cost-Effectiveness Analysis of 1,000 Strategies for the Provision of Adjuvant! Online, Oncotype DX, and Chemotherapy Poster HTAi 2011
Cost-effectiveness analysis and budget impact assessment: a graphical way to combine the two for the aid of decision makers Poster HTAi 2011
Investment and disinvestment of health technologies: the need for two cost-effectiveness thresholds Presentation HTAi 2011
Budget allocation and the revealed social rate of time preference for health Poster CADTH 2010
Does cost-effectiveness analysis discriminate against patients with short life expectancy? Poster HTAi 2010
You Can't Get Here From There: Methods for Cost Conversion Between Health Care Systems Need to Be Reexamined Presentation SMDM 2011
Investment and disinvestment of health technologies: the need for two cost-effectiveness thresholds Presentation SMDM 2011
Gene expression profiling for guiding adjuvant chemotherapy decisions in women with early breast cancer Presentation SMDM 2011
Cost-effectiveness of the most commonly used non-surgical treatments for non-specific (mechanical) neck pain Poster SMDM 2011
Cost-Effectiveness Of Non-Invasive Cardiac Imaging Technologies In Outpatients With Suspected Coronary Artery Disease Presentation SMDM 2011
Early Prevention of Pressure Ulcers Among Elderly Patients Admitted Through Emergency Departments: A Cost-Effectiveness Analysis Poster Canadian Association of Wound Care
Support Surfaces for Intraoperative Prevention of Pressure Ulcers in Patients Undergoing Surgery: A Cost-effectiveness Analysis Poster Canadian Association of Wound Care
Budget allocation and the revealed social rate of time preference for health Workingpaper THETA Working Paper
Does cost-effectiveness analysis discriminate against patients with short life expectancy? Matters of logic and matters of context Workingpaper THETA Working Paper
Some problems with the UK Treasury's discount rate Workingpaper THETA Working Paper




January 29, 2012 - © Toronto Health Economics and Technology Assessment Collaborative, 2007-2011